目的 随着中国式现代化文化建设全面推进与发展，西部文化作为西部地区的优势资源亟待焕活与创新。方法 从西部文化资源的多元信息整合视角出发，以文化资源创新融合及设计应用为目标，引入生命科学的双螺旋模型系统，以西部历史文化、民族民俗文化独立发展态势及二者融合发展为双链路径，对西部文化资源进行融合创新。结果 从文化资源选择、文化内容突破和文化设计建构三个层面，完成面向设计创新的文化资源双螺旋模型构建，并对模型展开完整的解构和系统化应用。结论 西部文化资源融合双螺旋模型从综合视角，立足于多元文化要素的协同共融，为西部文化创新高质量发展提供新的途径和参考，为西部文化创意产品设计注入新的思路与方法。

With the comprehensive advancement and development of Chinese-style modernization culture construction, western culture, as a valuable resource in the western region, urgently needs revitalization and innovation. Starting from the perspective of integrating diverse information from western cultural resources and aiming at innovation, fusion, and design application of cultural resources, a double helix model system from the field of life sciences was introduced. It took the independent development trends of western historical culture and ethnic folklore culture, as well as their converging development, as dual-chain pathways for the fusion and innovation of western cultural resources. Based on three levels of cultural resource selection, breakthrough in cultural content, and cultural design construction, a double helix model for cultural resource innovation, tailored for design purposes, was developed. The model was further deconstructed and systematically applied. The western cultural resource fusion double helix model, from a comprehensive perspective, is rooted in the collaborative integration of diverse cultural elements. It provides new avenues and references for the high-quality development of western cultural innovation and injects fresh perspectives and methodologies into the design of western cultural and creative products.