This paper aims to shorten the product design and development cycle, improve user’ satisfaction with medical games tutoring toys, and enhance the tutoring effect on medical games for children with tumor. Through literature research, field investigation and observation, expert group interviews and other methods, the users’ demand for medical game tutoring toys was understood and analyzed in detail, and the fuzzy analytic hierarchy process (FAHP) was used to summarize the multi-level factors that affect the design of medical game toys for children with tumors and set up the evaluation index model. The weight value of each evaluation index was calculated based on multiple rounds of questionnaire evaluation from the expert group to determine the importance order of each index factor, and then the fuzzy comprehensive evaluation of the product design indicators was made to obtain several factors that have the greatest influence on the design of medical game tutorship toys for children with tumor and the direction of design optimization. The evaluation results show that the most influential factors are the safety of material structure, psychological guidance, emotional care, applicability of medical procedures and ease of operation. Therefore, when developing and optimizing medical games tutoring toys for children with tumors, based on the comprehensive consideration of multiple factors in the design evaluation model, the above factors can be taken into special consideration to make products more suitable for user needs.