This paper focuses on the“living” design of products characterized by Poyang Lake regional culture to put forward innovative design methods of Poyang Lake Cultural and creative products, thus enhancing the cultural connotation of products and promoting the regional culture of Poyang Lake. With the establishment of design model diagram related to products characterized by Poyang Lake regional culture and the demonstration and verification of specific examples, the cultural and creative products not only had high-quality visual effect, but daily-use value as well as good user experience; not only obtained artistic quality, but emphasized the use-oriented philosophy. Based on the “living” perspective of cultural and creative products with the characteristics of regional culture in Poyang Lake, in compliance with the design principles of living transformation, authentic transmission of regional culture in Poyang Lake, cultural identity reconstruction, and establishment of cultural communication concept, the definite and viable methods and strategies were provided for the design of Poyang Lake cultural and creative products combined with examples. The practical demonstration of Poyang Lake cultural and creative products provides reference value for the design of current cultural and creative products, so that the material culture of Poyang Lake can be preserved and the non-material culture can be “living”, therefore achieving a win-win situation between cultural inheritance and cultural and creative product innovation.