The purpose of this paper is to study the design of the intangible cultural heritage APP interactive interface. First, literature research and competitive product analysis are used to screen out representative samples of intangible cultural heritage apps, and summarize three dimensions of visual presentation, functional attributes, and interactive experience. The key design elements and factor level are determined according to the three dimensions, and then 18 design combinations are determine through orthogonal experiment method. Quantify scores are got based on user needs and preferences. The design elements and the utility vaue and importance of each element level are calculated based on experimental data. The interface design principles of the intangible cultural heritage APP are established on this basis. Finall, the Qingsha Museum APP in Yuxian County is taken as an example for case analysis. Aiming at the problems of intangible cultural heritage apps and user preferences, the intangible cultural heritage APP interactive interface with the highest user satisfaction is designed. As a multi-factor statistical analysis method of data, the joint analysis method can enable designers to better understand the users' preferences for the intangible cultural heritage APP interactive interface, enhance user experience and user stickiness, thus achieving the spread of intangible cultural heritage and providing design ideas for similar APP interface design in the future.