In view of the diabetic foot for disease prevention and nursing, the relationship between emotion and product interaction design is explored, from the perspective of emotion intervention, by quantifying the user experience the emotional level combining with physical, psychological and behavior levels. A strategy of product innovation design based on emotion guided behavior interaction is proposed, and the reliability demonstration is carried out through the "WEICHU" prevention and treatment product design of diabetic foot. Focusing on user research, emotional information mining, data processing and analysis, combined with map of user experience research methods, based on the "emotional ring" and other relevant theories, SAM emotional scale was adopted to allow the subjects to evaluate their own emotions, quantify the emotional level in the experience map, and deeply mine the user emotional experiences in the disease process, to gain more reliable and accurate design opportunities, to optimize the user experience map interaction model, and from the aspects of user behavior to explore the emotional guidance and the relationship between product design, on the basis of structures, prevention and treatment diabetic foot function model of the product. The quantitative analysis of the causes and changes of patients' emotions and the emotional level in the experience process as the basis for the consideration of product interaction design is conducive to the construction of a benign interactive relationship and the effective improvement of the prevention and treatment experience of diabetic foot patients.