In order to make consumers further experience and feel the characteristic culture of Mulao ethnic group, improve the regional and cultural characteristics of the packaging of their characteristic agricultural products, forward constructive suggestions were put on the packaging design of Mulao ethnic group characteristic agricultural products. Take vitis quinquangularisis wine for example, the product packaging of it was collected and organized through the field investigation and Internet research. PEST model analysis was used to analysis the problems existing in packaging. Based on Mulam costume characteristic culture, the connotation and social value were excavated, and the elements of the clothing were analyzed, generalized, extracted. CGM model was used to design the packaging shape of wool wine, and the elements of color and pattern were effectively integrated to obtain the wool wine packaging with Mulao ethnic characteristics. Integrating Mulao ethnic costume culture into the packaging of local characteristic agricultural products will not only improve the cultural connotation of regional agricultural products, but also promote the inheritance and innovation of minority characteristic culture.