This paper aims todeeply excavate the cultural connotation of traditional hand weaving skills in Southeast Guangxi and explore the innovative application in household products design, so as to better protect and inherit the traditional hand weaving skills of ethnic minorities. The survival status and development difficulties of traditional hand weaving skills in Southeast Guangxi were analyzed through the application and analysis of modern household product design and exploring the integration strategy and research focus of traditional hand weaving skills and modern design. The comparative analysis method was used to compare the traditional hand weaving skills with modern technology, and the advantages of traditional hand weaving skills in culture, aesthetics and technology were obtained. Taking household design as a breakthrough, the advantages of traditional hand weaving skills were integrated into modern household design, and the principle of combining traditional modeling and fashion trend was explored. Integrating the connotative value of traditional hand weaving skills in Southeast Guangxi into modern household design can enable consumers to feel the cultural and technological value of traditional handicrafts in the experience of modern household products, which has important practical significance for the inheritance and dissemination of ethnic minority culture.