Under the background of the experience economy, the rapid iteration of apps leads to more conflicts between software novelty and usability. It is an urgent problem to explore how to strike a proper balance between them. This paper starts by defining the concepts of novelty and usability, systematically sorts out the different relationships between them, and summarizes and deduces the solutions with the methods of literature research and case analysis. In conclusion, three relationships between novelty and usability are obtained, and the construction method of the harmonious relationship between novelty and usability is proposed. There are three relationships between novelty and usability, namely conflict, incoherence and consistency. On this basis, the “4+3+1” auxiliary method system is proposed to bolster the harmonious relationship between novelty and usability, and the consistent trend framework of software novelty design is correspondingly set up, which provides reference and help for the enterprise’s software iteration and development.