In view of people's attention to health in the post-epidemic era, the paper aims to clear the importance of family air health, and explore new product design and methods to protect family air health. Firstly, the opportunity points of products in the post-epidemic era are analyzed from the view of economic, social and technological (SET) factors. Then through market survey, users' demands for disinfection products are collected, and combined with human science, the system elements related to products are stratified and sorted out. The function usage model is clarified, and samples are made with the help of the theoretical research of Kansei Engineering; Finally, the design concept and model are obtained, and the rationality of the design results is evaluated. Combining with the science of human affair and Kansei Engineering research method, the conceptual model of household air disinfection products in the post-epidemic era is obtained, and the process is scientific and feasible. This research further improves the methods of health product design in the post-epidemic era, and provides new ideas for the subsequent innovative design of related products.