The paper aims to explore the influence of multi-sensory information transmission on modern packaging design and the combination of the two ways and to analyze the feasible path of packaging design under multi-sensory experience. Emotional care for consumers is very important in packaging design, and the ways involved in packaging design are diversified. This paper first starts from the help of the sensory in the recognition of people's lives, affirming the impact of sensory experience on people's emotion, then introduces this kind of sensory-based expression to modern packaging design. pointing out that the people's perception of the packing is not limited to vision, but involving the recognition and exploration of the sense of touching, hearing, smelling and tasting in different degrees, so as to explore the path of modern packaging design based on multi-sensory expression. Finally from the connotation of multi-sensory expression, the paper explores the flexible attempt under the basic principles, summarizes the scientific application path and concludes the specific design methods. The packaging design works combining a variety of different sensory expressions can stimulate consumers' nerves at multiple levels and leave a deep impression in consumers' minds easily.