To study the development status of Qiang sheepskin drum under the integration of culture and tourism based on the Tea Horse Ancient Road, to provide methods and ideas for the innovative design of Qiang sheepskin drum which is lagging behind, and to realize the inheritance, development and innovative transformation of characteristic handicrafts in Qiang area, according to the demand survey of cultural products based on the development of Tea Horse Ancient Road, this paper analyzes the predicament and breakthrough direction of the development of Qiang sheepskin drum. To explore that the innovative development of Qiang sheepskin drum, strategies should be carried out to further strengthen the integration of culture and tourism, to enrich product types, to strengthen the exploration of characteristics, to enhance cultural creativity, to strengthen the development of materials and craft, to enhance the innovation of materials and technology, to reinforce the integration of science and technology, to heighten the innovation of digital products, etc. which will support to realize the innovative design of Qiang sheepskin drum. For the inheritance and innovative design of Qiang sheepskin drum based on the development of Tea Horse Ancient Road, take it root in Qiang's characteristic culture, and explore the product characteristics, aesthetic consciousness, cultural connotation and artistic form of sheepskin drum with modern design techniques, diversified cultural creative ideology and new materials and new technological innovations, so as to meet people's increasing cultural demands, to stimulate people's desire to buy, to drive product sales, to promote the living development of sheepskin drum in modern life and finally to realize the cultural value, tourism value and economic value of Qiang's traditional culture at present.