Aiming at the problem that it is very difficult for the visually impaired to take liquid medicine by themselves, the paper intends to design a kind of liquid medicine bottle for the visually impaired. The QFD theory is used to investigate the target users and get the weight of the user needs that meet the reliability requirements. The expert group transforms the user needs into technical characteristics and constructs the quality house of liquid medicine bottles for the visually impaired to obtain the technical characteristics ranking and the correlation. Then the TRIZ theory is used to transform the negative technical characteristics, choose the corresponding invention principle to solve the technical conflict. Considering the solution of technical conflict and the important technical characteristics, the liquid medicine bottle for the visually impaired is designed. Through the integration of QFD and TRIZ theory, a good liquid medicine bottle for the visually impaired can be designed for the visually impaired to take liquid medicine, enhance the self-care ability, and verify the effectiveness of QFD and TRIZ integrated design method in product innovation design.