The work aims to explore the aging design of the medical guidance system interface from the perspective of embodied cognition to optimize the interface availability and improve the interactive experience of elderly users. Based on the embodied cognitive theory, the characteristics of embodied interaction were summarized. Firstly, the aging design elements of product interface were refined from three aspects:functional purpose, interactive behavior and emotional performance. Secondly, the use experience and embodied cognitive behavior of elderly users in the use of medical guidance system were investigated and the behavior pain points of elderly users were mined by drawing the user experience map. Next, the embodied cognitive demands of users were obtained through the analysis on aging design elements and the design requirements of interface were put forward. Then, combined with the design level of medical guidance system, the aging design strategy of product interface was proposed, which was based on embodied cognition from the aspects of "situational" functional process, "vivid" interactive experience and "focused" emotional experience. Finally, the aging design practice of medical guidance system was carried out to verify the effectiveness of the aging design method. Physical experience, mental model and interaction between body and environment are important factors affecting cognitive understanding, so the cognitive abilities of elderly users in short-term memory, information analysis and decision-making will deteriorate. Therefore, the interaction design method established based on embodied cognition provides a feasible strategy for aging design to improve user experience.