The work aims to summarize the five spatial parameters of visibility, visible green index, space openness, spatial shape index and spatial information entropy on the basis of the aesthetic value of expressway landscape form and visual space perception elements and carry out visual landscape evaluation on the Si-Xiao Expressway in Yunnan Province, in order to improve the visual landscape quality along the expressway. GoPro camera was used to collect expressway landscapes, and PS software was applied to synthesize photos in the field of view of the human eye as the basic material for evaluation. With the help of GIS, OpenCV and other software, the dimensions of spatial parameters were considered. The spatial parameter structure of visual landscape of the Si-Xiao Expressway is extremely unbalanced. Some problems are found along the Si-Xiao Expressway, including insufficient recreation service facilities, poor plant maintenance in some sections, inadequate management and lack of local characteristics of landscape information along the expressway, etc. The evaluation of expressway visual landscape based on spatial parameters is the most active attempt to practice the research of expressway construction transformation in China. It can provide practical reference for expressway beautification and greening projects in Yunnan Province in the future, and can also provide reference for landscape planning and design of beautiful highways in China.