The work aims to design a collapsible isolation equipment that can provide on-site medical treatment environment, so as to reduce casualties caused by public safety emergencies, solve the problem of idle emergency isolation equipment in peacetime, and efficiently meet the daily medical treatment and emergency public safety treatment. The integrated INPD/AHP/TRIZ method was constructed to design and study the solution. The whole design process was based on the INPD method. Firstly, the design opportunity points of folding isolation equipment were found by SET analysis. Then a hierarchical structure model was established and AHP was used to calculate the weight and prioritize the equipment requirements. Then the TRIZ theory tool was used to solve the conflict between requirements, and the design concept matrix was combined to screen out superior design concepts and form the design scheme. Finally, the equipment model was established, the central control interface was designed, and the user survey was conducted again to verify whether the design scheme met the user's expectations. The folding isolation device could quickly provide a certain scale of high standard medical space. The INPD/AHP/TRIZ design process can provide insight into the fuzzy multiple demands of users, solve the contradictions in product design with different principles, and improve the ideas and directions for the innovative design research of related temporary isolation equipment.