The work aims to explore the information visualization design of traditional Chinese medicine culture in Tongchuan based on the concept of pathchwork art, so as to promote the combination and development of patchwork art and Chinese medicine culture. Literature review, investigative analysis and empirical methods were used to combine traditional Chinese medicine culture with expression techniques of patchwork art and integrate it into the information visualization design of characteristic traditional Chinese medicine culture in Tongchuan. The traditional Chinese medicine culture of Tongchuan was divided into four themes:the sources of medicine, the banquets of medicine, the instruments of medicine and the techniques of medicine, and the information visualization design with the regional connotation of Tongchuan was created by combining the patchwork art and Chinese medicine culture, showing the charm of traditional patchwork art and traditional Chinese medicine culture of Tongchuan. The integration of patchwork art and Tongchuan traditional Chinese medicine culture provides an innovative way for information visualization design and is expected to promote the publicity of traditional Chinese medicine cultural industry in Tongchuan and China.