The work aims to put focuses on the frame of a balance bike to reduce weight of balance bike frames through topology optimization while satisfying the strength and stiffness constraints of the model, so as to provide a reference for lightweight design of balance bike frames. First, a 3D model of the frame was created using SolidWorks. Then, static analysis of the original frame was conducted using ANSYS Workbench to obtain the stress distribution of the frame. Based on these results, topology optimization was performed on the original model using Altair Inspire, with the objective of reducing the frame weight. After topology optimization, a reconstructed model was obtained. Compared with the original frame, the weight of the optimized frame was reduced by approximately 54.0%. Although the von Mises stress of the optimized frame increased under the premise of meeting usage specifications, it was still less than the yield strength of the material, ensuring the safety and stability of the frame. This study effectively reduces the weight of the balance bike frame through topology optimization while maintaining the necessary structural strength and stiffness. Despite the increase in stress, it remains within the allowable range of the material, demonstrating the feasibility of topology optimization in the lightweight design of frames. This method provides new ideas and references for the future design and improvement of balance bike frame components.