In recent years, driven by Internet technology and artificial intelligence technology, the Chinese typeface design practice has entered a new stage of development in terms of communication media, application scenarios and presentation methods. By focusing on the internal relationship between key font technology changes and Chinese typeface design, the work aims to review the new technology, new concept and new aesthetic changes of Chinese typeface design practice in different stages since the emergence of the computer font library, and reflect the historical cross-section of the innovative practice direction and achievements of Chinese typeface design in different periods, providing theoretical support for the research of Chinese Typeface design. Literature study, case study and empirical study were used to investigate the influence of key font technology innovations on Chinese typeface design methods, styles and applications since the emergence of computer font library, and to demonstrate the linkage changes among Chinese typeface design technology, humanities and aesthetics. Every key technology innovation will stimulate the infinite vitality and possibility of Chinese typeface design practice, and influence the direction of Chinese typeface design and application. Adapting to the context of the times, combining the cultural origin of Chinese characters with new media, new needs and new ideas, the work outlines the visual picture of Chinese typeface design in the future.