Based on the requirements of the era of cultural and tourism integration, facing the dual cultural identity of the Tang Poetry Road in eastern Zhejiang, the work aims to explore the coupling symbiotic design strategy of landscape poetry image and tourism cultural and creative products of the Tang Poetry Road in eastern Zhejiang. Firstly, the literature analysis method was used to analyze the mutual proof relationship between landscape poetry and the Tang Poetry Road in eastern Zhejiang. Secondly, the comparative research method was used to analyze the symbolic coupling between the landscape poetry image and the tourism cultural and creative products of the Tang Poetry Road in eastern Zhejiang. Finally, by using the design empirical method and taking Tiantai Mountain as a case, the design symbiosis path of landscape poetry image in the tourism cultural and creative products of the Tang Poetry Road in eastern Zhejiang was constructed. Through the three dimensions of mutual proof relationship, symbolic coupling and design symbiosis, the coupling symbiosis design strategy of landscape poetry image and tourism cultural and creative products of the Tang Poetry Road in eastern Zhejiang was constructed. The essence of the integration of culture and tourism is two-way empowerment. The research on the coupling and symbiosis of landscape poetry image and tourism cultural and creative products in the Tang Poetry Road in eastern Zhejiang will have a two-way promoting effect on the design and dissemination of landscape poetry culture and the enrichment of tourism product formats in the Tang Poetry Road in eastern Zhejiang.