The work aims to explore drug packaging design strategies that can effectively prevent children from attempting to engage in dangerous opening behaviors in response to children's drug safety accidents. Based on the theory of driving force reduction, this article analyzed the behavioral motivations behind the safety accidents of children's medicines, clarified the logical relationship between "probability", internal driving force, triggers, and habit strength in the occurrence of accidents. It also identified the factors that could easily mislead children in drug packaging and proposed safety-oriented drug packaging design ideas to prevent dangerous behaviors in children. Ultimately, an implementable design strategy was constructed. The theory of driving force reduction reveals the underlying causes of children's drug safety accidents from three aspects:internal driving force, inducement, and habitual intensity. The attenuation of any element will reduce the occurrence probability of children's drug safety accidents. Therefore, enhancing visual, olfactory, tactile, motor, and intelligent obstruction design in drug packaging provides diversified guarantees for the safety of children's drugs.