The work aims to explore the communication path of Anhui logo "Bai Zhaoji" under the perspective of the Yangtze River culture, in order to promote brand activation and culture inheritance. Based on the profound heritage of the Yangtze River culture and the regional characteristics of Anhui, the communication path of the brand image of Anhui logo "Bai Zhaoji" under the perspective of the Yangtze River culture was investigated from the historical inheritance of the "Bai Zhaoji" brand, the analysis of the current situation of brand image communication, the visual and contextual and cross-border communication strategies, the integration practice of brand activation and culture inheritance, as well as the challenges and opportunities faced by multiple dimensions. A comprehensive communication mode of "visual communication layer + cultural context inheritance layer + cross-border cooperation layer + brand activation layer" was constructed, expounding that under the perspective of the Yangtze River culture, Anhui logo "Bai Zhaoji" realized effective brand image communication and in-depth mining of cultural value through multi-dimensional strategies, showing brand development path of "culture inheritance, brand innovation, market expansion and image enhancement". The study reveals the close relationship between regional culture and brand inheritance, shows the important role of cultural identity in promoting culture inheritance, enhancing brand value and promoting regional economic development, and provides a model and inspiration for the dissemination of regional cultural identity and brand activation.