The work aims to explore the application strategy of VR technology in the development and design of cultural and creative products, and provide more ideas for the design and development of cultural and creative products. The concepts of VR technology and cultural and creative products were expounded by literature and concept description. The application and development of cultural and creative products with VR technology were studied by case study. The application of VR technology and cultural and creative products in the fields of popular science, game and travel was studied. In conclusion, the application of VR technology is very extensive, including but not limited to games, movies, education, medical, military, architectural design, tourism, etc. It is feasible to apply VR technology to the development of cultural and creative products. In the future development of cultural and reactive products, VR technology will be more widely used. Therefore, designers should make full use of VR technology, design and develop more innovative cultural and creative products, give consumers a more authentic experience, to bring people a good technological experience of smart life.