| 孙剑飞,包斯元.磁性纳米颗粒介导的电磁神经治疗的最新进展[J].包装工程,2021,42(4):34-44. |
| 磁性纳米颗粒介导的电磁神经治疗的最新进展 |
| Recent Progress on Electromagnetic Nerve Therapy Mediated by Magnetic Nanoparticles |
| 投稿时间：2020-11-05 |
| DOI：10.19554/j.cnki.1001-3563.2021.04.004 |
| 中文关键词: 磁性纳米颗粒 经颅磁刺激 神经系统疾病 神经调节 |
| 英文关键词: magnetic nanoparticle transcranial magnetic stimulation nervous system disease neuromodulation |
| 基金项目:国家自然科学基金“神经导航rTMS刺激视觉皮层个体化快速抗抑郁及其机制和生物学标记研究”(81830040) |
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| 中文摘要: |
| 目的 介绍磁性纳米颗粒的性质和生物医学应用，以及通过磁性纳米颗粒介导的电磁神经刺激治疗的最新进展。为今后优化刺激参数、提高磁神经刺激效率提供参考。方法 总结近年来国内外对磁性纳米颗粒的研究进展，并重点分析基于磁性纳米颗粒的神经磁刺激方法及效果。结果 磁性纳米颗粒具有成像、靶向给药、磁热疗等生物医学应用，以磁性纳米颗粒为基础进行神经磁刺激的类型可分为磁热刺激、磁电刺激及磁机械力刺激三种。这种刺激方式安全、高效且精准性高，能够改善传统磁刺激方式的缺陷。结论 磁性纳米颗粒性质独特，是近年来研究最多、发展速度最快的纳米材料之一。利用磁性纳米颗粒介导的神经磁刺激具有广阔的应用前景。 |
| 英文摘要: |
| The work aims to introduce the properties and biomedical applications of magnetic nanoparticles, and the latest progress of electromagnetic nerve stimulation therapy mediated by magnetic nanoparticles, so as to provide reference for optimizing stimulation parameters and improving the efficiency of magnetic nerve stimulation in the future. The research progress of magnetic nanoparticles at home and abroad in recent years was summarized, and the methods and effects of neuromagnetic stimulation based on magnetic nanoparticles were emphatically analyzed. Magnetic nanoparticles had biomedical applications such as imaging, targeted administration and magnetic hyperthermia. The types of neuromagnetic stimulation based on magnetic nanoparticles can be divided into three types:magnetic-thermal stimulation, magneto-electrical stimulation and magnetic-mechanical stimulation. This stimulation method was safe, efficient and accurate, which can improve the defects of traditional magnetic stimulation. Magnetic nanoparticles have unique properties. It is one of the nanometer materials and one of the most studied and fastest developing nanomaterials in recent years. Neuromagnetic stimulation mediated by magnetic nanoparticles has broad prospects of application. |
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